Comparative study of 1, 2 Naphthoquinone oximes and their Cu (II) metal chelates

V.V. Dhapte

Abstract


Isomeric Cu (II) metal chelates with 1, 2 Naphthoquinone 1-oxime, 1, 2 Naphthoquinone 2-oxime and 1, 2 Naphthoquinone dioxime were synthesized and their comparative study were carried out with respect to their physical and chemical properties. The ligands and Cu (II) metal chelates were characterized by using electronic spectra, FT-IR, and elemental analysis and confirmed the composition of ligands and metal chelates. The FT-IR spectra of metal chelates and ligands (using KBr pellets in the range 4000-400 cm-1) indicated that the isomeric chelates retain their identity even after chelation. In electronic spectra, BET and QET bands showed variation in wavelength after chelation. The compounds were studied for antimicrobial activity against Gram positive bacteria (Staphylococcus aureus, Bacillus substilus) and Gram negative bacteria (Escherichia coli, Proteus vulgaris). Among all these ligands and metal chelates, 1, 2 Naphthoquinone dioxime showed comparatively more antimicrobial activity against Escherichia coli and Staphylococcus aureus.


Keywords


1, 2 Naphthoquinone 1-oxime, 1, 2 Naphthoquinone 2-oxime, 1, 2 Naphthoquinone dioxime, Staphylococcus aureus, Bacillus substilus, Escherichia coli, Proteus vulgaris.

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