Use of Magnesium Sulphate Infusion In Tetanus Therapy

Waseem Abbas, Aaqib javaid, Muhammad Awais aziz


Objective: For effective control of seizure continuous muscle relaxation is required. Magnesium Sulphate is one of the most important and effective drug which helps in control of seizure.

Design of Study: Observational study (Prospective)

Setting: North Medicine Ward Mayo Hospital Lahore.

Patients and Methods: Every patient from June 2017 to January 2018 was treated with magnesium sulphate and deep tendon reflex was checked for everyone.

Results:  A Total of 40 cases were contemplated with average age of 36 years. Among them 15 were females and 25 males. Male to female ratio was 1.6:1.Normal incubation period was 16 days. Twenty cases showed improvement from the disease. Females had higher rate of mortality of 20% than those of males 8%. Septic abortion was the highest risk factor that caused resistance to therapy. Seven patients were admitted to hospital due to resistance and were put on the ventilator which expired later on.

Conclusion:  In patients with tetanus having muscular spasm Magnesium Sulphate is very efficient and cost effective as well. 


Lock Jaw, Spasm, Tetanus.

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