Ischemic Stroke and Increased Homocysteine Level

Ayesha Ashraf, Ariba Shafiq Chishti, Sofia Ali Sana


Objective: The main aim of this study was to find the correlation between ischemic stroke and increased homocysteine levels.

Type of Study: It is a cross sectional type of study.

Place and Duration of study: This study was carried out in a duration of 15 months from February 2018 April 2019 in medical departments of Jinnah Hospital Lahore.

Materials and Methods: A total of 100 patients were included in this study. The patients included in this study were between the ages of 40 to 80 years. Both genders were selected randomly. CT brain plain was obtained in all these patients and diagnosis of ischemic infarction was made of the basis of presence of hypo dense area. Blood samples were taken from all the patients and sent for homocysteine levels and the value of 15 µmol/L was labeled as high.

Results: Out study included 100 patients with 40(40%) females and 60(60%) males. 52.34± 6.57 years was the mean age. 60% cases had increased homocysteine levels and frequency was much higher in female patients which was found to be affecting 24(63.15%) cases. The frequency was much higher in people with increased age ranging between 60 to 80 years where it was found to be 65.38%.

Conclusion: One of the most fatal complications caused by increased homocysteine levels is ischemic stroke and the incidence is much higher in people with increased age ranging between 60 to 80 years.


Stroke, Ischemia, raised homocysteine

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