Analysis of stone formation related to metabolic diseases and urinary tract infection

Shah Jahan, Hassan Manzoor, Namra Masud


Objective. The main aim of this was to find the relation between stone formation in metabolic diseases and urinary tract infection caused by it.

Place and Duration of study: This study was carried out in urology department of Sheikh Zaid hospital Lahore in a duration of 9 months from March 2019 to November 2019.

Materials and Methods: A total of 100 patients were included in this study. Both genders were selected randomly. Every patient was asked to collect the urine sample for 24 hours which was then sent to a reliable laboratory for analysis of specific gravity, PH, uric acid, creatinine, calcium oxalate, phosphate, magnesium and citrate. Detailed history of each patient was taken. Plastic boxes which were inert were used to collect the samples and then stored at 2-8 ºC. Blood samples were also sent to look for the levels of creatinine, phosphate, urea, uric acid and calcium.

Results: Among the 100 patients selected 65 were females and 35 were male patients with the mean age of 38 years. 79% of the patients presented with the complaint of lumbar pain which was followed by burning micturition and hematuria. Ureteric of renal stones were diagnosed in 94% of the patients. Recurrent stone formation was seen in 38% of the cases while 62% of the patients suffered from it for the first time. Calcium oxalate was seen in 82.5% of the cases after detailed chemical analysis.

Conclusion: The results obtained from our study shows that incidence of stone formation is very high in patients who have metabolic abnormalities and hypocitraturia, hyperoxaluria and hypercalciuria are the commonest abnormalities seen


Metabolic abnormalities, Urinary tract infection, urolithiasis

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